We designed the Zeta Plus™ Encapsulated System Scale-Up Filter Capsules with LA Media as single-use depth filtration capsules for the bioprocessing industry where upstream cell culture clarification or downstream impurity removal is required. The encapsulated lenticular design and vertical flow path help provide consistent performance between formats.
3M™ Zeta Plus™ Encapsulated System Filter Capsule with LA Series Media is used for clarification of bioprocess, biological and pharmaceutical fluids.
Our LA media has a positive charge to provide higher reduction of negatively charged contaminants compared to a mechanical filtration mechanism alone.
Pharmaceutical Grade Media
3M Zeta Plus Encapsulated System Capsules, with LA Series Media are manufactured to controls described in our Drug Master File on record with the FDA. Certificates of Quality are included with every filter. These filters meet the requirements of USP Class VI Biological Reactivity Tests and meet the strict requirements specified in the Drug Master File, including product control and traceability.
Encapsulating High Performance
Scale-up capsules are available in three sizes to meet varying volumes and applications and the capsules have been designed for minimal hold-up volume.
The production capsule manifolds have 1.5 in. sanitary connections on the inlet and outlet. 3M Zeta Plus Production capsules may be used in a multi-stage filtration or purification train with a single 3M Encapsulated System holder. One of the stages may include 3M™ Emphaze™ products. A pair of manifolds is required between each stage of the multi-stage train within the 3M Encapsulated System holder.
Combined with the larger production scale capsules, 3M Zeta Plus Encapsulated System offers a completely single-use depth filter solution to process from 100 ml to 25,000 L of liquid.